Sorry, I couldn't resist the pun, but podcasting is the new craze sweeping the interweb. I've set up a feed from the Anewmusic blog and we have a couple of snippets posted as test files. The next step will be to begin broadcasting :))

From the few highly unscientific tests I've carried out on my laptop here's how I rate the following free podcast clients for PC:

doppler
Well featured, clean interface with good support for text sections of feeds. Not always so hot at pulling feeds though - I've had more errors with this than the others.

nimiq
Nice compact client. Very simple. No support for non-audio enclosures that I've found yet. Works well though.

ipodder
We like ipodder. Not quite as simple as nimiq and lacks some of the features of doppler, but it comes in the most flavours and has worked consistently well.

So which am I recommending? Well for simplicity nimiq, for features doppler, but for all round ease of use it has to be ipodder (by a whisker).